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Detroit R&D Oxidative Stress ELISA (8-isoprostane) Kit

Our popular 8-isoprostane Oxidative Stress Kit is for the determination of 8-isoprostane levels in biological samples or wastewater. This competitive ELISA kit is suitable for the analysis of 24-triplicate samples. Range = 1 to 10,000 pg/mL.

Recent References Using our 8-isoprostane ELISA:

 1.Trares, K. et al. Associations of urinary 8-iso-prostaglandin F2a levels with all cause dementia, Alzheimer's disease, and vascular dementia incidence: results from a prospective cohort study. Alzheimer's Dement 16: 804-813. 2020. PMID: 32281305 Individuals with increased 8-isoprostane levels and the AOE e4/e4 genotype had an increased dementia risk.

 2. Kayamba, V. et al. Biomass smoke exposure is associated with gastric cancer and probably mediated via oxidative stress and DNA damage: A case-control study. JCO Global Oncology 2020 :6, 532-541. 2020. PMID: 32228314 Exposure to biomass smoke resulted in increased levels of 8-isoprostane in a case-control study.

3. Schottker, B et al. Oxidatively damaged DNA/RNA and 8-isoprostane levels are associated with the development of type 2 diabetes at older age: Results from a large cohort study. Diabetes Care, doi: 10.2337/dc19-1379. 2020. PMID: 31653645. At older ages, an imbalanced redox system resulting from reduced cellular repair capacity contributes to the development of type 2 diabetes

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