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Hypertension as a result of an increase in arachidonic acid (AA) ω-hydroxylase (20-HETE synthesis) activity of cytochrome P450s CYP4A, CYP4F, and CYP1B1 is well established. Thus, 20-HETE has become a biomarker and therapeutic target for hypertension and stroke. This ELISA kit is suitable for measuring 20-HETE in up to 24 biological samples in-triplicate.

New References Using Our 20-HETE ELISA

1 .Bou-Fakhredin, Read More

Detroit R&D provides researchers with several assays that can assess the state of mitochondrial homeostasis:

Catalog # MCN1    Read More

Soluble epoxide hydrolase (sEH) is a key enzyme in the arachidonic pathway due to it’s ability to biotransform anti-hypertensive epoxyeicosa-trienoic acids (EETs) to dihydroxyeicosatrienoic acids (DHETs) thereby making soluble epoxide hydrolase an important pharmacological target. 

This colorimetric ELISA assay kit is suitable for measurements of sEH enzyme activity in tissues and cells (cell lysates or media) using the substrate 14,15-EET.. 

Additionally, the assay kit Read More