Tools to Assess Mitochondrial
Function and Disease
Detroit R&D provides researchers with several assays that can assess the state of mitochondrial homeostasis.
Santos, JM et al. (2018) The role of mitochondrial DNA damage at skeletal muscle oxidative stress on the development of type 2 diabetes. Molecular and Cellular Biochemistry DOI: 10.1007/s11010-018-3361-5
Yi, C-X et al. (2017) TNFa drives mitochondrial stress in POMC neurons in obesity. Nature communications [DOI: 10.1038/ncomms15143]. PMID: 28489068
Horikawa, I et al. (2017) D133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells. Cell Death and Differentiation, 24(6): 1017-1028. PMID: 28362428
Santos, JM et al. (2016) Can regular exercise reverse modification in skeletal muscle induced by high fat diet and decreased insulin secretion? Diabetes 65, A194.